Need Help Choosing a Charity?

  • Start by asking yourself, “What’s important to me?” Think about people in your life, your hobbies and interests, and things you would like to change or are concerned about.
  • Review the Charity Listing in the Giving Guide or use the search engine below to search by service area, location and more to find a charity you'd like to support.
  • Click here to view a virtual map of 2021 participating charities.
  • Donate using ePledge or our Adobe Digital Pledge Form. The form will automatically open in your web browser. Please download and open with an Adobe program to utilize the "submit" button, or save and email to
Charity NameCodeFederation / GroupDescription
Alex’s Lemonade Stand Fndn.1973America's Best Charities - FederationA four-year-old cancer patient's frontyard lemonade stand evolved to a nationwide movement to find a cure for pediatric cancer. Every person can make a difference.
American Fndn. for Children with AIDS2920America's Best Charities - FederationHIV+ children don't have to die. Help us provide life-saving medicine, medical equipment, nutritional supplements, livestock, seeds, and hope to children affected by AIDS.
Childhood Cancer Research for a Cure2961America's Best Charities - FederationWorldwide, a child is diagnosed with cancer every two minutes, and in the U.S., more children are lost to cancer than any other disease.
Children’s Cancer Aid & Research Inst.2007America's Best Charities - FederationProvides childhood cancer research grants. Ships medical supplies and humanitarian aid to programs that treat childhood cancer and other degenerative diseases. Love the children!
Children’s Cancer Assistance Fund2425CHC: Creating Healthier Communities - FederationChildhood cancer can be devastating for any family. With our help, no family has to endure the costs and heartache of pediatric cancer alone.
Children’s Cancer Partners of the Carolinas4020Independent AgencyWe do this by providing financial, logistical and emotional assistance ensuring every child access to lifesaving treatment, regardless how far/often required, until age 21.
Children’s Flight of Hope1070CHC: Creating Healthier Communities - FederationChildren's Flight of Hope provides sick children with free air transportation to medical care that will save, prolong, or improve the quality of their lives.
Children’s Hospital of the King’s Daughters1470-006United Way Federation - Albemarle AreaCHKD provides a continuum of inpatient and outpatient pediatric medical services for children and families throughout southeast Virginia, the Eastern Shore, and northeast North Carolina.
Children’s House at Johns Hopkins Hospital1638America's Best Charities - FederationProvides a warm "home away from home" for families in the midst of a medical crisis so their critically ill children may focus on healing.
Children’s Medical Ministries1940America's Best Charities - FederationCompassionate healthcare volunteers providing free wheelchairs, rehabilitation equipment, medical clinics, healthcare instruction, dental services, food and clothing to children in despair. Active in disaster relief.
Children’s Organ Transplant Assoc.2056America's Best Charities - FederationCOTA gives hope to children and young adults who need a life-saving organ transplant by providing fundraising assistance and family support.
Duke Children’s Hospital & Health Ctr.1569Independent AgencyDuke Children’s provides the most advanced medical treatment & research available in a compassionate, family-centered environment for children from the Southeast & around the world.
Make-A-Wish Fndn., Central & Western NC3779Independent AgencyOur mission is to grant life-changing wishes to children with critical illnesses. We serve 51 counties in NC from Alamance westward.
National Pediatric Cancer Fndn.5104America's Best Charities - FederationDedicated to funding research that will lead to less toxic and more targeted therapies to eliminate childhood cancer worldwide.
Pediatric Brain Tumor Fndn. of the US5044America's Best Charities - FederationFunds medical research for childhood brain tumors. Offers free patient family support services, funds scholarships for survivors, provides advocacy for cause.
Ronald McDonald House, Chapel Hill1524Independent AgencyThe Ronald McDonald House of Chapel Hill provides a “home-away-from-home” for families of seriously ill and injured children receiving treatment at area hospitals.
Ronald McDonald House, Charlotte3732Independent AgencyRMH of Charlotte provides a safe, affordable and caring "home-away-from-home" for families with seriously ill or injured children who travel to Charlotte for medical treatment.
Ronald McDonald House, Eastern NC Greenville1526Independent AgencyThe Ronald McDonald Houses of Eastern North Carolina provide a temporary home, support and access to medical care for families of children who are receiving treatment from area medical facilities.
Ronald McDonald House, Piedmont Triad2517Independent AgencyThe Ronald McDonald House of Winston-Salem, Inc. provides temporary housing, food, and a support network for families who bring their seriously ill children to Forsyth County for medical treatment.
Shriners Hospitals for Children5011America's Best Charities - FederationChildren suffering from burns, spinal cord injuries, and orthopedic conditions receive world-class medical care in a family-centered environment regardless of ability to pay.
St. Jude Children’s Research Hospital1026CHC: Creating Healthier Communities - FederationResearches and treats childhood cancer and other life-threatening diseases. Families never billed by St. Jude for treatment, travel, housing or food. Discoveries freely shared worldwide.